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4.8 · 30 verified reviews

27,000+ customers across Europe

MasterCell

Firmer, brighter, calmer — every morning.

Highly-concentrated niacinamide day serum with plant stem cells.

Niacinamide-rich Plant stem cells Triple hydration Barrier repair
  • Highly-concentrated niacinamide — 2nd INCI position, real results
  • 17 clean ingredients — the shortest INCI list in the range
  • €0 risk — 30-day money-back if your skin doesn't love it
Purchase frequency

One tin = your complete 28-day reset (30 daily doses)

Less than the price of a coffee — clinical-grade anti-aging.

Free shipping on orders over €100

  • 30-Day Money-Back Guarantee
  • Dermatologically approved
  • Made in Germany
  • Vegan & Cruelty-Free
Description

A potent anti-aging day serum built around highly-concentrated niacinamide (Vitamin B3, second INCI position) and plant stem cells. Reduces fine lines, boosts collagen, strengthens the barrier, and brightens skin tone — without the heavy or sticky feel of most anti-aging serums.

Format: 30 ml glass bottle · 5 ml trial size also available.
Made in Germany · Physician formulated · Dermatologically approved · Vegan & cruelty-free.

Key Ingredients & Full INCI

Niacinamide (Vitamin B3): Highly concentrated — 2nd INCI position. Strengthens barrier, reduces pores, regulates sebum, smooths fine lines, brightens.

Acetyl Glucosamine: Stimulates your skin's own hyaluronic-acid synthesis. Synergistic with niacinamide for brightening + cell renewal.

Plant Stem Cells (Aloe Barbadensis Powder) + Lactic Acid: Gentle AHA + concentrated cell-regeneration for smoother texture.

3-Layer Hydration (Glycerin + Sodium Lactate + Panthenol): Skin-identical humectant, NMF binder, and barrier-strengthening Vitamin B5.

Licorice Root (Dipotassium Glycyrrhizate) + Zinc PCA: One of the strongest natural anti-inflammatories + sebum control + antimicrobial defence.

Full INCI: Aqua, Nicotinamide, Propanediol, Acetyl Glucosamine, Glycerin, Sodium Lactate, Dipotassium Glycyrrhizate, Aloe Barbadensis Leaf Juice Powder, Zinc PCA, Panthenol, Sorbitan Caprylate, Tocopherol, Potassium Sorbate, Xanthan Gum, Helianthus Annuus Seed Oil, Lactic Acid, Capryloyl/Caproyl Methyl Glucamide.

17 clean ingredients — the cleanest serum formula in the klarskin range. No filler, no fragrance, no parabens, no silicones.

How to Use

1. Start with clean, dry skin — toner optional.
2. Press 2–3 drops between palms, then gently pat onto face and neck.
3. Let it sink in for 1–2 minutes.
4. AM: follow with GlowScreen SPF50+ to seal in hydration and protect.
5. PM: follow with RetinGold for the 24/7 anti-aging duo.

Suitable for all skin types — including sensitive. Use daily for best results.

Free-From & Certifications
  • ✓ Vegan
  • ✓ Cruelty-free
  • ✓ Fragrance-free
  • ✓ Paraben-free
  • ✓ Silicone-free
  • ✓ Sulfate-free
  • ✓ No harsh alcohols
  • ✓ Allergen-free
  • ✓ BPA-free glass packaging
  • ✓ Plastic-free & recyclable
  • ✓ Made in Germany — Physician formulated — Dermatologically approved
Shipping & Returns

Free shipping on EU orders over €100. Standard delivery 3–5 business days. International shipping available.

30-day money-back guarantee — if your skin doesn't love it, email us within 30 days for a full refund. No questions asked.

AS SEEN IN

Best for: a healthy gut and glowing skin.
[Klarskin is] the place to go after you've tried everything else for acne.
This supplement delivers the minerals your skin needs to protect cells from oxidative stress.
Among the best dietary supplements on the market today.
Originally developed with acne-prone skin in mind, Klarskin's Radiance Powder is the first part in a three-part routine designed to help your complexion glow.
Winner of the Douglas #FORWARDBEAUTYChallenge 2018.

WHAT YOU'LL EXPERIENCE

Anti-aging,without the routine overhaul.

Most anti-aging serums are either too heavy, too harsh, or too complicated. MasterCell does the work of three — barrier, brightening, anti-aging — in one lightweight step.

Visibly firmer + plumper

Plant stem cells + acetyl glucosamine stimulate collagen and your skin's own hyaluronic-acid production. Fine lines soften, skin feels bouncy.

Visible texture change in 2–3 weeks. Significant anti-aging at 6–8 weeks.

Brighter, more even tone

Niacinamide + acetyl glucosamine work synergistically to inhibit tyrosinase — less hyperpigmentation, more glow, more even skin tone.

One of the most-researched brightening combinations in dermatology.

Deep hydration, no heavy feel

A three-layer hydration system (glycerin, sodium lactate, panthenol) plumps your skin without the sticky residue most anti-aging serums leave.

Sinks in fast. Doesn't pill under makeup or SPF.

A stronger skin barrier

Niacinamide, licorice root, panthenol — all proven barrier rebuilders. Less redness, less reactivity, less of the things that make your skin feel fragile.

Suitable for sensitive and reactive skin. Calms while it strengthens.

HOW IT WORKS · WHAT IT DOES

Four mechanisms.One lightweight serum.

MasterCell is not a one-trick serum. Each of the four pillars targets a different driver of skin aging — barrier weakness, pigment, dehydration, inflammation — and they reinforce each other.

THE FORMULA PILLARS

  • Highly-concentrated B3

    Niacinamide sits at the 2nd INCI position — clinical-grade concentration. Multitasks across pores, sebum, fine lines, pigmentation, and barrier.

  • Cell renewal

    Plant stem cells (aloe), acetyl glucosamine, and gentle lactic acid AHA work together — your skin's natural turnover, accelerated.

  • Triple hydration

    Glycerin draws water in, sodium lactate locks it down in the corneal layer, panthenol seals everything with a healing finish.

  • Calm + repair

    Licorice root (one of nature's strongest anti-inflammatories) + zinc PCA + Vitamin E. Reactive skin becomes resilient skin.

THE PROOF

17
Clean ingredients
★4.9
312+ verified reviews
2nd
INCI position (high niacinamide)
6–8 wk
For visible anti-aging

*Physician formulated. Dermatologically approved. Made in Germany. Suitable for all skin types including sensitive.

VS THE ALTERNATIVES

Most niacinamide serumsdon't do this much.

Single-active drugstore serums or expensive luxury complications — MasterCell sits in between. Real concentration, clean formula, sensible price.

OTC Niacinamide
Drugstore Anti-Age
Luxury Anti-Age
★ BESTMasterCell
High niacinamide concentration
High niacinamide concentration
High niacinamide concentration
High niacinamide concentration
High niacinamide concentration
Plant stem cells (cell renewal)
Plant stem cells (cell renewal)
Plant stem cells (cell renewal)
Plant stem cells (cell renewal)
Plant stem cells (cell renewal)
Gentle AHA included
Gentle AHA included
Gentle AHA included
Gentle AHA included
Gentle AHA included
Anti-inflammatory (licorice root)
Anti-inflammatory (licorice root)
Anti-inflammatory (licorice root)
Anti-inflammatory (licorice root)
Anti-inflammatory (licorice root)
Clean formula (<20 ingredients)
Clean formula (<20 ingredients)
Clean formula (<20 ingredients)
Clean formula (<20 ingredients)
Clean formula (<20 ingredients)
Fragrance-free
Fragrance-free
Fragrance-free
Fragrance-free
Fragrance-free
Safe for sensitive skin
Safe for sensitive skin
Safe for sensitive skin
Safe for sensitive skin
Safe for sensitive skin
Under €50 / month
Under €50 / month
Under €50 / month
Under €50 / month
Under €50 / month
— Antoneta, Founder of klarskin

THE FOUNDER

I created MasterCell because skincareshouldn't feel like a part-time job.

For years I followed 10-step routines, layered serums on serums, and watched my skin get more reactive, not more resilient.

So we built MasterCell with the same German pharmacist team behind Radiance Powder — one serum, 17 ingredients, every one of them earning its place. Niacinamide at clinical concentration, plant stem cells for renewal, licorice root to calm everything down.

It's the serum that does the work of three — so your routine can do less, and your skin can do more.

— Antoneta, Founder of klarskin

Try MasterCell

€37.90 / month · Subscribe & save

Read her full story

THE ACTIVES

17 ingredients.Zero filler.

MasterCell has the shortest INCI list of any klarskin serum. Every single one of the 17 ingredients does a job — and the four pillars below show how.

Vitamin B3 at clinical concentration

Niacinamide is one of the most-studied actives in dermatology — and concentration matters. MasterCell uses it at the 2nd INCI position (right after water), supported by complementary actives.

Niacinamide

Vitamin B3 (Nicotinamide)

Strengthens barrier, reduces pores + sebum, smooths fine lines, brightens.

Acetyl Glucosamine

Amino sugar

Triggers your skin's own hyaluronic acid synthesis. Synergistic brightener.

Propanediol

Plant-derived humectant

Boosts penetration of all other actives. Light, non-tacky feel.

Zinc PCA

Zinc + NMF

Regulates sebum, antimicrobial, NMF component.

Plant stem cells + gentle AHA

Cell turnover slows with age. These four actives gently accelerate it — without the irritation of stronger acids.

Aloe Powder

Aloe Barbadensis

Concentrated plant stem cells. Higher actives density than aloe gel.

Lactic Acid

α-hydroxy acid

Gentle AHA. Boosts turnover AND hydrates (unlike glycolic).

Tocopherol

Vitamin E

Antioxidant + cell protection. Stabilises other actives.

Sunflower Oil

Helianthus Annuus

Linoleic acid + Vitamin E. Non-comedogenic barrier support.

A three-layer hydration system

Most anti-aging serums forget hydration. MasterCell stacks three different humectants for plump, bouncy skin all day.

Glycerin

Vegetable glycerin

Draws water from the environment into your skin. Body-identical humectant.

Sodium Lactate

NMF component

Natural NMF component. Binds water in the corneal layer. Regulates pH.

Panthenol

Pro-Vitamin B5

Converts to Vit B5 in skin. Speeds renewal, soothes, seals hydration.

Xanthan Gum

Polysaccharide film

Forms a light moisture film. Stabilises the whole formula.

For skin that overreacts

Reactive skin needs calm before it can rebuild. These actives reduce inflammation and strengthen the barrier — at the same time.

Licorice Root

Dipotassium Glycyrrhizate

One of the strongest natural anti-inflammatories. Calms redness, soothes irritation.

Zinc PCA

Zinc + NMF

Antimicrobial, sebum-balancing, supports skin immune response.

Vitamin E

Tocopherol

Neutralises free radicals from UV and pollution. Protects lipids.

Panthenol

Pro-Vitamin B5

Medical-grade barrier repair (the Bepanthen ingredient).

REAL RESULTS

312+ women trust MasterCell.The highest-rated serum in the range.

312+
Verified reviews
★ 4.9
Average rating
17
Clean ingredients

YOUR DAILY ROUTINE

One serum.AM + PM, the work is done.

Use MasterCell as the base of your routine. Then GlowScreen during the day, or RetinGold at night. Three drops. No part-time job.

  1. 01

    Cleanse, then 2–3 drops

    Start with clean, dry skin. Press 2–3 drops between your palms. Apply MasterCell as the first serum in your routine, AM and PM.

  2. 02

    Pat into face + neck

    Gently pat the serum into face and neck — don't rub. Let it absorb for 1–2 minutes. You'll feel the dewy finish, not a sticky one.

  3. 03

    Layer SPF or retinol on top

    AM: follow with GlowScreen SPF50+ to seal in hydration and protect.
    PM: follow with RetinGold for 24/7 anti-aging.

WHAT TO EXPECT

Week 1–2

Skin feels softer, plumper, calmer. Hydration shows up immediately. Less reactivity.

Week 3–4

Texture refines. Pore appearance reduces. First signs of brightening, even tone.

Week 6–8

Visible anti-aging: fine lines softened, firmness returns, barrier visibly stronger.

FREQUENTLY ASKED

Questions, answered.

From what age should I start using MasterCell?

MasterCell is designed for ages 25+ — when fine lines first appear and skin starts losing density. The niacinamide, plant stem cells, and acetyl glucosamine address early aging at the cellular level before it becomes visible.

Can I use it with retinol?

Yes — but separate them by time. MasterCell goes on in the morning, RetinGold at night. That way you get the niacinamide-strengthening barrier benefit in the AM, and the retinol cell-renewal benefit in the PM. The two are designed as a 24/7 anti-aging duo.

Is it safe for sensitive skin?

Yes — actively beneficial. The licorice root (Dipotassium Glycyrrhizate) is one of the strongest natural anti-inflammatories in cosmetic science. Panthenol soothes. The formula is fragrance-free, allergen-free, alcohol-free.

How long until I see results?

Texture and hydration: 2–3 weeks. Brightening + even tone: 4 weeks. Visible anti-aging (fine lines softened, firmness): 6–8 weeks. Use daily and consistently.

How does it feel on the skin?

Light, fast-absorbing, never sticky. Most anti-aging serums sit heavy or pill under SPF and makeup — MasterCell sinks in within minutes and leaves a dewy, plump finish that layers perfectly.

Can I use it under makeup?

Absolutely. Press the serum on, wait 1–2 minutes, then continue with SPF and makeup. It creates a plumping base that makes foundation sit better.

Is it really only 17 ingredients?

Yes — that's the cleanest formula in the entire klarskin range. RetinGold has 36, GlowScreen has 16 (but needs UV filters). Every one of MasterCell's 17 ingredients has a documented job. No filler, no fragrance, no silicones.

What if it doesn't work for me?

30-day money-back guarantee. If your skin doesn't love it within 30 days, email us — we'll refund your first order in full. No questions asked.

See all FAQs

COMPLETE THE ROUTINE

AM, PM, inside-out.Pair MasterCell with the rest of the system.

MasterCell is the base. Add GlowScreen for daytime protection, RetinGold for nighttime correction, and Radiance Powder for gut-skin support.

Configure a routine collection or add products via the Customizer.